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雷红涛

发布时间:2020-06-12文章来源:食品学院浏览次数:6668


姓名

雷红涛

性别

邮箱地址

hongtao@scau.edu.cn

通讯地址

广东广州五山华南农业大学食品学院

联系电话

020-85283925

所在院系

食品学院

职称

教授

担任职务

院长

个人简介

博士,二级教授,博士生导师,现任华南农业大学食品学院院长,入选国家高层次人才特殊支持计划创新领军人才、国家创新人才推进计划中青年科技创新领军人才、“广东特支计划”科技创新领军人才。兼任教育部高等学校食品科学与工程类专业教学指导委员会副主任委员、食品质量与安全工作组组长,中国农业工程学会农产品加工与贮藏工程专业委员会副理事长,广东省药学会手性药物专委会副主任,广东省食品与包装机械行业协会技术标准委员会副主任,Springer刊物Chemical and Biological Technologies in Agriculture(JCR Q1)副编辑,Food and Agricultural Immunology、农业工程学报、食品科学、食品与发酵工业、食品工业科技、食品安全检测学报、食品与生物技术学报、食品与发酵科技等刊物编委。

研究方向

食品安全,分子识别及应用。旨在利用食品科学、免疫学、结构生物学、分析化学、毒理学等多种手段,研究食品污染物的生物分析方法、分子识别机制、食品毒理、检测产品研制等,为保障食品安全提供科技支撑。

承担教学

食品营养学,免疫检测技术,食品分析

科研项目

主持“十三五”国家重点研发计划项目、国家自然科学基金重点项目、行业公益(农业)项目、广东省自然科学基金团队项目等多项。

学术论文

  1. Tian Guan, Jianfei He, Dayu Liu, Zaoqing Liang, Bowen Shu, Yiping Chen, Yingju Liu, Xing Shen, Xiangmei Li, Yuanming Sun, Hongtao Lei*. Open surface droplet microfluidic magnetosensor for microcystin-LR monitoring in reservoir. 2020. Analytical Chemistry,92(4), 3409–3416

  2. Ning Lu, Li Ling, Tian Guan, Lanteng Wang, Dian Wang, Jiahui Zhou, Ting Ruan, Xing Shen, Xiangmei Li, Yuanming Sun, Hongtao Lei*. Broad-specificity ELISA with a heterogeneous strategy for sensitive detection of microcystins and nodularin. 2020. Toxicon. 175(2), 44–48

  3. Xing Shen, Jiahong Chen, Shuwei Lv, Xiulan Sun, Boris Dzantiev, Sergei A. Eremin, Anatoly V. Zherdev, Jianfa Xu, Yuanming Sun, Hongtao Lei*. Fluorescence polarization immunoassay for determination of enrofloxacin in pork liver and chicken. 2019. Molecule. 24(24), 4462

  4. Xiangmei Li, Xinze Wu, Jin Wang, Qicheng Hua, Jinxiao Wu, Xing Shen, Yuanming Sun, Hongtao Lei*. Three lateral flow immunochromatographic assays based on different nanoparticle probes for on-site detection of tylosin and tilmicosin in milk and pork. 2019.Sensors and Actuators B: Chemical. 301(12), 127059–127068

  5. Tian Guan, Wenzheng Huang, Ningxia Xu, Zhenzhen Xu, Lelun Jiang, Mengting Li, Xiaoqun Wei, Yingju Liu, Xing Shen, Xiangmei Li, Changqing Yi*, Hongtao Lei*. Point-of-need detection of microcystin-LR using a smartphone-controlled electrochemical analyzer. 2019.Sensors and Actuators B: Chemical. 294,132-140

  6. Xiangmei Li, Jin Wang, Changqing Yi, Lelun Jiang, Jinxiao Wu, Xiaomin Chen, Xing Shen, Hongtao Lei*. A smartphone-based quantitative detection device integrated with latex microsphere immunochromatography for on-site detection of zearalenone in cereals and feed. 2019. Sensors and Actuators B: Chemical. 290(1), 170–179

  7. Xiangmei Li, Xiaomin Chen, Xinze Wu, Jin Wang, Zhiwei Liu, Yuanming Sun, Xing Shen, Hongtao Lei*. Rapid detection of adulteration of dehydroepiandrosterone in slimming products by competitive indirect enzyme-linked immunosorbent assay and lateral flow immunochromatography. 2019. Food and Agricultural Immunology, 30 (1), 123-139

  8. Hongtao Mu, Shaohuan Chen, Fengyin Liu, Jianbo Xiao, HuiHuang, Yuhua Zhang, Yuanming Sun, Xiangyang Gao, Hongtao Lei*, Xuewen Yuan*. Stereoselective Interactions of Lactic Acid Enantiomers with HSA: spectroscopy and docking application. 2019.Food Chemistry, 270(1), 429-435

  9. Taotao Qiu, Xing Shen, Xiangmei Li, Yunyun Gong, Zhongmin Zou, Chunhong Liu, Feng Ye, Chenyang Mi, Zhenlin Xu, Yuanming Sun, Jie Lin†, Huidong Zhang, and Hongtao Lei*. Egg Yolk Immunoglobulin supplementation prevents rat liver from Aflatoxin B1-induced oxidative damage and genotoxicity. 2018. Journal of Agricultural and Food Chemistry, 66(50),13260–13267

  10. Jing Wu,Yunlei Xianyu, Xiangfeng Wang, Dehua Hu, Zhitao Zhao, Ning Lu, Meng-Xia Xie*, Hongtao Lei*, Yiping Chen*. An enzyme-free amplification strategy for biosensing using Fe3+- polyglutamic acid coordination chemistry. Analytical Chemistry. 2018, 90(7), 4725-4732

  11. Aori Qileng, Jie Wei, Ning Lu, Weipeng Liu, Yue Cai, Minshi Chen, Hongtao Lei*, Yingju Liu*. Broad-Specificity Photoelectrochemical Immunoassay for the Simultaneous Detection of Ochratoxin A, Ochratoxin B and Ochratoxin C. Biosensors & Bioelectronics, 2018, 106, 219–226

  12. Lanteng Wang,Wenmeng Jiang, Xing Shen, Xiangmei Li, Xinan Huang, Zhenlin Xu, Yuanming Sun, Shun-Wan Chan, Lingwen Zeng, Sergei Alexandrovich Eremin, Hongtao Lei*. Four Hapten Spacer Sites Modulating Class Specificity: Non-directional Multianalyte Immunoassay for 31 β-agonists and Analogues. 2018. Analytical Chemistry, 90(4), 2716–2724

  13. Taotao Qiu, Xing Shen, Zhen Tian, Riming Huang, Xiangmei Li, Juan Wang, Rong Wang, Yiguo Jiang, Hongtao Lei*, Huidong Zhang*. IgY reduces AFB1-induced cytotoxicity, cellular dysfunction, and genotoxicity in human L-02 hepatocytes and Swan 71 trophoblasts. 2018. Journal of Agricultural and Food Chemistry. 66(6), 1543–1550

  14. Hongtao Mu, Zhenlin Xu, Yingju Liu, Yuanming Sun, Baoling Wang, Xiulan Sun, Zhanhui Wang, Sergei A. Eremin, Anatly V. Zherdev, Boris B. Dzantiev, Hongtao Lei*. Probing the stereoselective interaction of ofloxacin enantiomers with corresponding monoclonal antibodies by multiple spectrometry. 2018.Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. 194, 83–91

  15. Yao Liu, Lan-Teng Wang, Kai Zhou, Sergei A. Eremin, Xin-An Huang,Yuan-Ming Sun, Zhen-Lin Xu & Hong-Tao Lei. Rapid and homologous immunoassayfor the detection of herbicide propisochlor in water. 2018.Food and Agricultural Immunology29(1), 67–83

  16. Xing Shen, Jiahong Chen, Xiangmei Li, Hongtao Lei*, Xinan Huang, Sergei A. Eremin, Cuihua Wu, Aijuan Jia*. Monoclonal antibody based homogeneous immunoassay for three banned agonists and molecular modeling insight. 2017.Food and Agricultural Immunology, 28(6), 1438–1449

  17. Yaqiong Zhang, Lanteng Wang, Xing Shen, Xiaoqun Wei, Xinan Huang*, Yingju Liu*, Xiulan Sun, Zhanhui Wang, Yuanming Sun, Zhenlin Xu, Sergei Alexandrovich Eremin, HongtaoLei*. Broad-specificity immunoassay for simultaneous detection of ochratoxins A, B and C in millet and maize.2017.Journal of Agricultural and Food Chemistry65(23), 4830–4838

  18. Jiahong Chen,Lanteng Wang, Lanlan Lu, Xing Shen, Xin-an Huang, Yingju Liu, Xiulan Sun, Zhanhui Wang, Sergei Alexandrovich Eremin,Yuanming Sun, Zhenlin Xu, Hongtao Lei*.Four specific hapten conformations dominating antibody specificity: quantitative structure-activity relationship analysis for quinolone immunoassay. 2017. Analytical Chemistry, 89(12), 6740-6748

  19. Yong-fang Li, Yuan-ming Sun, Ross C. Beier, Hongtao Lei*, Shirley Gee, Bruce D. Hammock, Hong Wang, Zhan-hui Wang, Xiu-lan Sun, Yu-Dong Shen, Jin-Yi Yang, Zhen-Lin Xu*. Immunochemical techniques for multianalyte analysis of chemical residues in food and the environment: A review. TrAC Trends Anal Chem. 2017. 88, 25-40

  20. Jiahong Chen, Ning Lu, Xing Shen, Qiushi Tang, Chijian Zhang, Jun Xu, Yuanming Sun, Xin-an Huang,* Zhenlin Xu,* Hongtao Lei*. Investigation of an immunoassay with broad specificity to quinolone drugs by genetic algorithm with linear assignment of hypermolecular alignment of data sets and advanced quantitative structure−Activity relationship analysis. Journal of Agricultural and Food Chemistry, 2016. 64(13), 2772–2779

  21. Haopeng Zeng, Jiahong Chen, Chijian Zhang, Xinan Huang*, Yuanming Sun, Zhenlin Xu*Hongtao Lei*. Broad-Specificity chemiluminescence enzyme immunoassay for (Fluoro)quinolones: hapten design and molecular modeling study of antibody recognition. Analytical Chemistry. 2016, 88(7), 3909–3916

  22. Jiahong Chen, Ilya A. Shanin, Shuwei Lv, Qiang Wang, Chuanbin Mao, Zhenlin Xu, Yuanming Sun, Qing Wu, Sergei A. Eremin*Hongtao Lei*. Heterologous strategy enhancing the sensitivity of the fluorescence polarization immunoassay of clinafloxacin in goat milk. Journal of the Science of Food and Agriculture, 2016, 96(4),1341–1346

  23. Yao Liu, Xuan Zhang, Chunhong Liu, Ruili Yang, Zhenlin Xu, Lijun Zhou*, Yuanming Sun*Hongtao Lei*.Enantioselective and synergetic toxicity of axial chiral herbicide propisochlor to SP2/0 myeloma cells.Journal of Agricultural and Food Chemistry, 2015,63(36), 7914–7920

  24. Zuyu He, Shuai Zang, Yingju Liu*, Yuan He, Hongtao Lei*.A multi-walled carbon nanotubes-poly(l-lysine) modified enantioselective immunosensor for ofloxacin by using multi-enzyme-labeled gold nanoflower as signal Enhancer. Biosensors & Bioelectronics, 2015, 73(11), 85–92 (一区,IF 7.780)

  25. Chijian Zhang, Hongtao Lei*, Xiaolong Huang, Kai Cai, Zhenlin Xu, Yuanming Sun. Preparative resolution of gatifloxacin enantiomers with pre-column esterification strategy and comparing their enantioselectivity to bacteria and antibody. Biomedical and Environmental Sciences, 2015, 28(2),157–160

  26. Hongtao Mu, Baoling Wang, Zhen-Lin Xu, Yuan-Ming Sun, Xin-an Huang, Yudong Shen, Sergei Eremin, Anatoly Zherdev, Boris Dzantiev*Hongtao Lei*. Stereospecific recognition and quantitative structure-activity relationship between antibodies and enantiomers: ofloxacin as model hapten. Analyst, 2015, 140(2), 1037–1045

  27. Jiahong Chen, Shuwei Lv, Qiang Wang, Zhenlin Xu, Jinyi Yang, Yudong Shen, Hong Wang, Yuanming Sun, Hongtao Lei*. A Specific and High-Throughput Fluorescence Polarization Immunoassay for Surveillance Screening of Clinafloxacin in Milk. Food Analytical Methods, 2015, 8(6), 1468–1476

  28. Jin-Yi Yang, Yan Zhang, Hong Wang, Zhen-Lin Xu, Sergei A. Ereminb, Yu-Dong Shen, Qing Wu, Hong-Tao Lei*, Yuan-Ming Sun*. Development of fluorescence polarisation immunoassay for carbofuran in food and environmental water samplesFood and Agricultural Immunology. 2015, 26(3), 340–355

  29. Hongtao Mu, Hongtao Lei*, Baoling Wang, Zhenlin Xu, Chijian Zhang,Li Ling, Yuanxin Tian, Jinsheng Hu,Yuanming Sun*. Molecular Modelling Application on Hapten Epitope Prediction: An Enantioselective Immunoassay for Ofloxacin Optical Isomers. Journal of Agricultural and Food Chemistry, 2014, 62(31), 78047812

  30. Xuan Zhang, Qiang Wang, Zhong Yu, Sergei A. Eremin, Chunfai Yu, Jin Liu, Yuanming Sun, Hongtao Lei*. Antibody Production for a Rapid Fluorescence Polarization Immunoassay of EstroneBiomedical and Environment Science,2014, 27(1), 5255

  31. Shuai Zang, Yingju Liu*, Mouhong Lin, Jianli Kang, Yuanming Sun, Hong-Tao Lei *. A dual amplified electrochemical immunosensor for ofloxacin: Polypyrrole film-Au nanocluster as the matrix and multi-enzyme-antibody functionalized gold nanorod as the label. Electrochimica Acta,2013, 90 (2) 246253

  32. Hongtao Lei, Gang Xue, Chunfai Yu, Simon A. Haughey, Sergei A. Eremin, Yuanming Sun, Zhanhui Wang, Zhenlin Xu, Hong Wang, Yudong Shen, Qing Wu. Fluorescence polarization as a tool for the detection of a widely used herbicide, butachlor, in polluted waters. Analytical Methods, 2011, 3(10), 23342340.

  33. Qiang Wang, Simon A. Haughey, Yuan-Ming Sun, Sergei A. Eremin, Zhen-Feng Li, Hui Liu, Zhen-Lin Xu, Yu-Dong Shen, Hong-Tao Lei *. Development of a fluorescence polarization immunoassay for the detection of melamine in milk and milk powder. Analytical and Bioanalytical Chemistry, 2011, 399(6), 22752284.

  34. Hongtao Lei, Rui Su, Simon A Haughey, Qiang Wang, Zhenlin Xu, Jinyi Yang, Yudong Shen, Hong Wang, Yueming Jiang, Yuanming Sun. Development of a Specifically Enhanced Enzyme-Linked Immunosorbent Assay for the Detection of Melamine in Milk. Molecules, 2011, 16(7), 55915603

  35. Hongtao Lei, Jin Liu, Lijun Song, Yudong Shen, Simon. A. Haughey, Haoxian Guo, Jinyi Yang, Zhenlin Xu, Yueming Jiang, Yuanming Sun*. Development of a highly sensitive and specific immunoassay for determining chrysoidine, a banned dye, in soybean milk film. Molecules, 2011, 16(8), 70437057.

  36. Hongtao Lei, Yudong Shen, Lijun Song, Jinyi Yang, Olivier P. Chevallier, Simon A. Haughey, Hong Wang, Yuanming Sun*, Christopher T. Elliott*. Hapten synthesis and antibody production for the development of a melamine immunoassay. Analytica Chimica Acta, 2010, 665(1), 8490

  37. Yi Xu, Peng Zhong, Aimin Jiang*, Xing Shen, Xiangmei Li, Zhenlin Xu, Yudong Shen, Yuanming Sun, Hongtao Lei*. Raman spectroscopy coupled with chemometrics for food authentication: A review. 2020. Trends in Analytical Chemistry. https://doi.org/10.1016/j.trac.

  38. Tian Guan, Dayu Liu, Xiangmei Li, BowenShu, Mengting Li, Yingju Liu, Zhenlin Xu, Yudong Shen, Yuanming Sun, Hongtao Lei*, Xing Shen*. Magnet-actuated droplet microfluidic immunosensor coupled with gel imager for detection of microcystin-LR in aquatic products. 2020. Talanta, 219, 121329

  39. Zhiwei Liu, Qicheng Hua, Jin Wang, Zaoqing Liang, Jinhao Li, Jinxiao Wu, Xing Shen, Hongtao Lei*, Xiangmei Li*. A smartphone-based dual detection mode device integrated with two lateral flow immunoassays for multiplex mycotoxins in cereals. 2020. Biosensors and Bioelectronics, 158, 112178.

  40. Jin Wang, Xing Shen, Peng Zhong, Zhaodong Li, Qiushi Tang, Xinan Huang, Anatoly V. Zherdev, Boris B. Dzantiev, Sergei A. Eremin, Zhili Xiao, Hongtao Lei*, Xiangmei Li*. Heterologous immunoassay strategy for enhancing detection sensitivity of banned dye rhodamine B in fraudulent food. 2021. Chemical and Biological Technologies in Agriculture, 8(1): 17-26


获奖情况

获教育部高等学校科学研究优秀成果奖(科学技术)技术发明一等奖(第1)、国家科技进步二等奖(第2)、国家教学成果二等奖(第3)、广东省科学技术一等奖(第2)、中华农业科技二等奖(第2)各1项。

专利

  1. 雷红涛,张雅琼,沈兴,陆宁,徐振林,孙远明,杨金易,肖治理. 黄曲霉毒素B1半抗原、人工抗原及其卵黄抗体的制备方法,发明专利,ZL201610875386.X,申请日:2016.10.08;授权日:2018.11.27

  2. 雷红涛,张雅琼,孙远明,沈兴,陆宁,徐振林,沈玉栋,杨金易. 一种新型小分子结构及其在检测蓝绿藻肝毒素方面的应用,发明专利,ZL 201710224738.X,申请日:2017.09.15;授权日:2018.09.18

  3. 雷红涛,陈佳虹,卢蓝蓝,孙远明,徐振林,杨金易,沈玉栋,王弘,肖治理.一种吡哌酸的ELISA检测方法及应用.发明专利,ZL201510351080.X,申请日:2015.06.24;授权日:2017.07.11

  4. 雷红涛,孙远明,唐秋实,王弘,沈玉栋,杨金易,徐振林.一种罗丹明BELISA检测方法,发明专利,ZL201310077177.7,申请日:2013.03.12;授权日:2015.02.02

  5. 雷红涛,孙远明,刘信嘉,王弘,沈玉栋,徐振林,发明专利,卡那霉素A酶联适配体检测方法及应用,发明专利,ZL201310206129.3,申请日:2013.05.29;授权日:2014.12.17

  6. 雷红涛,孙远明,宋利军,刘瑾,王强.碱性橙半抗原、人工抗原和抗体及其制备方法和应用,发明专利,ZL201010256944.7。申请日:2010.08.17,授权日:2013.12.25

  7. 雷红涛,孙远明,王强,黄启欣.一种三聚氰胺抗原及其制备方法和应用,发明专利,ZL201010613333.3。申请日:2010.12.30,授权日:2012.12.26

  8. 雷红涛,孙远明,石敏,沈玉栋,杨金易,王弘,徐晓艳.去氢表雄酮半抗原、人工抗原和抗体及其制备方法和应用,发明专利,ZL200910039021.3。申请日:2009.04.27;授权日:2012.07.18

  9. 雷红涛,孙远明,薛刚,吴青,沈玉栋,张挺,杨金易,王弘.丁草胺极化荧光免疫检测方法,发明专利,ZL200810029088.4,申请日:2008.06.27;授权日:2012.05.20

  10. 雷红涛,孙远明,石敏,沈玉栋,张挺,杨金易,王弘,徐晓艳.一种保健品中去氢表雄酮的前处理方法,发明专利,中国,ZL200910039019.6,申请日:2009.04.27;授权日:2011.11.16

  11. 雷红涛,黄晓钰.快速检测有机磷农药残留的鱼酯酶试剂,发明专利号ZL02115152.0。申请日:2002.04.27;授权日:2005.03.23

  12. 雷红涛,孙远明,吴青,王弘,肖治理,沈玉栋,杨金易,黄晓钰.一种地西泮胶体金免疫检测试纸,实用新型专利,ZL200620062036.3,申请日:2006.07.25;授权日:2007.8.29

  13. 雷红涛孙远明黄晓钰王弘潘科吴青谌国莲,青霉素快速半定量检测试纸.发明专利ZL200520056967.8,申请日:2005.04.15;授权日:2007.11.28

  14. 雷红涛孙远明黄晓钰王弘潘科吴青肖治理谌国莲,庆大霉素快速半定量检测试纸.发明专利ZL200520056965.9,申请日:2005.04.15;授权日:2007.12.05

  15. 雷红涛,孙远明黄晓钰王弘潘科吴青谌国莲. 链霉素快速半定量检测试纸,发明专利,ZL200520056966.3,申请日:2005.04.15;授权日: 2007.12.05

  16. 雷红涛,许晶晶,沈兴,徐振林,孙远明,杨金易,沈玉栋,王弘,肖治理. 一种异丙甲草胺手性半抗原、人工抗原和抗体及其制备方法和应用. ZL 2019 1 0300552. 7. 申请日:2019.04.15;授权日:2021.03.12日

  17. 雷红涛,张雅琼,沈兴,陆宁,徐振林,孙远明,杨金易,肖治理. 一种簇选择性赭曲霉毒素人工抗原及其广谱性多克隆抗体的制备方法. 发明专利,ZL 201610876473,申请日:2016.10.08;授权日:2020.02.04

  18. 雷红涛,关甜,何剑飞,梁平力,李向梅,沈兴,杨金易,肖治理,徐振林,孙远明. 一种微囊藻毒素的生物传感器,实用新型专利,ZL 201920716443. 9,申请日:2019.05.17;授权日:2020.06.12